A journey along the TIM23 complex, the major protein translocase of the mitochondrial inner membrane

Authors

  • Umut Günsel BMC – Physiological Chemistry, LMU Munich, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany
  • Dejana Mokranjac BMC – Physiological Chemistry, LMU Munich, Großhadernerstr. 9, 82152 Planegg-Martinsried, Germany

Keywords:

mitochondria, protein translocation, protein sorting, targeting signal, presequence, TIM23 complex

Abstract

Proper structure and function of mitochondria depends on translocation of over a thousand different mitochondrial proteins from the cytosol. Mitochondrial proteins carry a number of different targeting signals and are translocated into the mitochondria by a number of different protein translocases. Here, we provide an overview of mitochondrial protein translocation pathways, and focus on the TIM23 complex, the major protein translocase of the mitochondrial inner membrane.

Downloads

Published

2020-02-27

How to Cite

Günsel, U., & Mokranjac, D. (2020). A journey along the TIM23 complex, the major protein translocase of the mitochondrial inner membrane. Biologia Serbica, 41(2). Retrieved from https://journal.pmf.uns.ac.rs/index.php/biologiaserbica/article/view/86

Issue

Vol. 41 No. 2 (2019): Biologia Serbica

Section

Review paper